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Antibody Response in Children to COVID-19 Stronger Than Adults, Hopkins Study – CBS Baltimore

BALTIMORE (WJZ) – According to a study by researchers at the Johns Hopkins Bloomberg School of Public Health, young children who have been infected with COVID-19 have much higher levels of antibodies against the virus than adults.

The researchers say the findings could help effectively immunize children under the age of 5 against COVID-19.

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The study was funded by the US Centers for Disease Control and Prevention previous report Low antibody response in already infected children.

The researchers analyzed samples taken from 682 people aged 0 to 62 years from 175 households in Maryland. Those households participated in a surveillance study from November 2020 to March 2021, and none of the participants had been vaccinated.

The researchers found evidence of COVID-19 antibodies in 56 people at the time of their study, indicating prior COVID-19 infection. Of those people, 15 were children aged 0 to 4, and 13 were children aged 5 to 17.

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Antibodies to a key site on the virus’ “external spike protein,” the researchers said, were 13 times higher in children aged 0-4 years and nearly 9 times higher in children. children from 5 to 17 years old.

The researchers found that levels of antibodies that neutralize SARS-CoV-2, which can be an indicator of protection against severe COVID infection, were almost twice as high in children aged 0-4 years compared with Adults.

“This study demonstrates that even children in the first few years of life are capable of developing robust antibody responses to SARS-CoV-2 infection, in some cases exceeding human responses. large,” Ruth Karron, MD, principal investigator and professor. in the Department of International Health and is director of the Johns Hopkins Vaccine Initiative at the Bloomberg School.

The school says children under 5 years of age are a relatively poorly studied population, and understanding the antibody response to SARS-CoV-2 at different ages can inform strategies and policies. COVID-19 vaccine book.

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“The very young children in our study developed high antibody titers to the SARS-CoV-2 mutant protein, which is the target antigen of the COVID vaccine,” said Karron. “These findings should provide some reassurance that with the right vaccine doses we can effectively immunize very young children against SARS-CoV-2.”

https://baltimore.cbslocal.com/2022/03/22/childrens-antibody-responses-to-covid-19-stronger-than-adults-hopkins-study-finds/ Antibody Response in Children to COVID-19 Stronger Than Adults, Hopkins Study – CBS Baltimore

Jake Nichol

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